Preheat your oven to 375°F (190°C). Line a rimmed baking sheet with parchment paper.
In a large bowl, whisk together the milk, beaten eggs, garlic powder, onion powder, salt, black pepper, caraway seeds, and fresh parsley.
Add the ground beef to the bowl. Using your hands, gently mix until the wet ingredients and seasonings are just combined with the meat. Do not overmix.
Transfer the meat mixture to the prepared baking sheet. Pat it down into a large, even rectangle about 1/2 inch thick.
Sprinkle the shredded cheese evenly down the center of the rectangle, leaving about a 1-inch border of meat around the edges.
Carefully lift the sides of the meat rectangle and fold them over the cheese, pinching the seams and the ends completely shut to seal the cheese inside. Shape into a neat loaf.
In a small bowl, whisk together the ketchup and Worcestershire sauce. Use a brush to coat the top and sides of the loaf evenly with the glaze.
Bake for 55 to 60 minutes, or until a meat thermometer inserted into the center reads 160°F (71°C).
Remove from the oven and let the loaf rest for 10 minutes before slicing to ensure the cheese stays inside.